Basic dilution : Distilled sterilized water 3cc + Lidocaine 1cc (total 4cc)

It is the best to use it all right after dilution. If you can not use it all, you need to keep it refrigerated and use it as soon as possible. Shake it enough to mix solution well when you re-use.
(Air injection during dilution may cause bacterial infection.)

We recommend you to puncture with 20G needle and use 21G~25G cannula for injection.

You can see improvement of skin tone after treatment. After 4weeks, you can see natural volume through collagen stimulation.

PDO is a safety-approved material that is used for more than 30 years in the world. Therefore, Safety and biodegradability of PDO are well recognized globally. Allergic and inflammatory reaction may occur in some cases. In that case you need to prescribe Phenyramine and NSAID. We recommend you to always prescribe antibiotics after procedure.

Collagen stimulation and regeneration continues for 2~12weeks, and PDO eventually degrades 6months after the treatment. We recommend you to undergo another Ultracol treatment in 3~5months for longer effect.

It takes 4~8 weeks for the collagen to be produced. And the long or longer presence of PCL and PLLA components inside the skin does not mean collagen production takes place continuously. Rather, the risk of side effects such as Nodule, paternity, and inflammatory reactions increases.

You can do treatment all over the area of face. Since there are no side effects, the thin skin area can be treated as well. You can usually treat forehead wrinkles, under eye wrinkles and nasolabial folds. The injection layer is the dermis and subcutaneous layer.

2~2.5million PDO Microspheres produces Collagen in dermis layer. It gives natural lifting effect and improvement of wrinkle and skin tone.

PDO threads degrade after 6months and produces Collagen in dermis layer. PDO Thread lifting is safe and effective treatment as well since it’s composed with PDO which is safe material. Ultracol PDO filler functions as same as PDO threads. 2millions PDO microspheres has same surface area with 1,400pcs of PDO mono threads. And it reduces treatment time, pain of patients, inflammatory reaction and treatment cost.

In case of PLLA and PCL, it takes about 2 years to be degraded completely. For this reason, the possibility of side effect like nodule and granuloma might be higher than Ultracol. When repeated treatment is done, the possibility of side effect will be much more increased because they will be overlapped with the undegraded powder. Sometimes they are not degraded after 2 years and then it is necessary to remove by operation.

HA filler is generally most used filler. However, composition of Hyaluronic acid is very low as only 2% and 98% is BDDE, which is cross-linker. BDDE has the possibility of danger since it has toxicity. In addition, HA filler has the strong character to pull water and it is advantageous to maintain the shape as viscosity of gel type. On the other hand, it has high risk of necrosis if it blocks or moves in the blood vessel. HA filler has the side effect that it is not degraded or skin is uneven after 1 year when large amount is injected. Therefore removal operation is reported frequently.

The size of PDO Microsphere of Ultracol is average 50μm so the nodule does not occur. During 8~12 weeks after treatment it produces collagen and PDO degrades in 6months. Therefore you do not need to dissolve it. It is similar with Botox that its mechanism of action is short and side effect is low.

You should use 20G needle. If you use 18G, foreign substance might be added.

When blood vessels are blocked by HA filler or excessive volume is injected, Hyaluronidase is used to remove HA filler. However, Ultracol does not have risk to block blood vessels. It is not necessary to dissolve it because it just stimulates collagen through PDO microspheres in dermal layer to create natural volume. Sculptra and Ellanse take more than 2 years to be degraded, resulting in side effects and removal by operation. However, PDO is much safer than PCL and PLLA because it is degraded within 3~6 months completely.

PDO is hydrophilic. When injecting, it is adsorbed onto dermal layer immediately and stays well in injected area, not flowing.

Comparing the composition of Sculptra and Ellanse, Ultra Col contains 3 times more particles. Also, surface area of one vial of Ultracol is equivalent to 1,400pcs of PDO Mono threads. Therefore it is cost-effective product comparing to Sculptra or Ellanse.

PDO is not a surface erosion, but a bulk erosion that hydrolyzes over a certain period of time. After 4~8 weeks which is required for collagen production, it safely degrades and disappears within 3-6 months without any inflammatory reaction.

AestheFill is a PLA filler in a porous spherical shape. Due to the porous structure, it can not maintain the spherical shape and become broken or clumped state. It is difficult to produce effective collagen.

There is another Korean PDO filler product manufactured by physical shredding. However, there are reports that the inflammatory reaction is severe due to the sharp crushed surface. And it can not be used in Korea as it is an unlicensed product in Korea. Ultracol is the world’s first and only product of PDO Microsphere type with Korean license.